Three people were killed after a car crashed into a building in Pittsburgh on Saturday, the city’s public safety department said.

The building — a plasma clinic — caught on fire, and the blaze has since been extinguished, according to ABC Pittsburgh affiliate WTAE-TV.

Ten employees and five donors were in the plasma clinic at the time, public safety director Wendell Hissrich told the Pittsburgh Post-Gazette.

Several people were injured, including one in critical condition, Hissrich told the newspaper.